What it is

ChromoMap is a safe, easy, and reliable noninvasive prenatal screen (NIPS) that uses a small sample of your blood to screen your pregnancy for common chromosome abnormalities like Down syndrome.

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Why It Matters

Chromosomes are structures that carry our genetic information, providing the instructions for the body to develop, grow, and function. A chromosome abnormality, or aneuploidy, occurs when each cell in the body has an extra or missing chromosome, which can cause developmental issues such as intellectual disability and birth defects or can result in miscarriage.

The ChromoMap screenSerenity NIPT looks for the most common chromosome abnormalities including Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome), and Trisomy 13 (Patau syndrome).

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Who It’s For

NIPS/NIPT is appropriate for women who are at least 10 weeks pregnant and interested in finding out more about the the health of her pregnancy.

Every woman is at risk of having a pregnancy affected with a chromosome abnormality, regardless of age or family history. Experts recommend that all women have prenatal screening during pregnancy. ChromoMap NIPS is appropriate for any woman at least 10 weeks pregnant who is interested in finding out more about the health of her pregnancy.

Some women may be at a higher risk for having a pregnancy impacted by a chromosome abnormality, including those:

  • Over 35 years old
  • Designated ‘high-risk’ by other prenatal testing
  • With a personal or family history of chromosome abnormalities

How it works

During pregnancy, small amounts of your baby’s genetic material pass through the placenta into your bloodstream. The ChromoMap screenSerenity NIPT uses a small sample of your blood in order to screen your pregnancy for the most common chromosome abnormalities, like Down syndrome.

In this test, blood is drawn from the mother, and the baby's DNA is identified and tested for abnormalities.

Noninvasive prenatal screens like ChromoMap have been shown to perform better than traditional prenatal screening methods, and they avoid the risk of miscarriage associated with invasive diagnostic procedures like amniocentesis and chorionic villus sampling (CVS).

Once your results are available, they will be shared with your healthcare provider, and you’ll have the opportunity to review them with an expert genetic counselor.

What to Expect from ChromoMap Genetic Counseling

Noninvasive prenatal tests like Serenity NIPT have been shown to perform better than traditional prenatal screening methods, and they avoid the risk of miscarriage associated with invasive diagnostic procedures like amniocentesis and chorionic villus sampling (CVS).


ChromoMap NIPS is a screening test. Diagnostic tests such as amniocentesis or CVS are available to confirm results. However, because these tests are invasive, they carry a risk of complications, including miscarriage.